World’s largest steam-sterilizable separator CSE 170

With a capacity of up to max. 10,000 litres of fermentation broth per hour, the new CSE clarifier of GEA Westfalia Separator is currently the largest steam-sterilizable centrifuge in the world. The new development focuses entirely on the safety of biotechnology processes and the efficiency of recovering active ingredients. Separators from GEA Westfalia Separator are used in biotechnology for processing animal cell cultures, recovering pharmaceutical proteins and vaccines, making hormones such as insulin, fractionating human blood plasma and also recovering many other pharmaceutical active ingredients.

In order to meet the high safety requirements applicable for production processes in biotechnology, the CSE 170 has numerous special features which stand for high valuable substance yields, gentle product treatment as well as optimum SIP and CIP capability.

Full sterilization concept with hydrohermetic feed
For sterilization purposes, GEA Westfalia Separator focuses exclusively on the full sterilization concept in which the entire installation including the separator is sterilized. Unlike the situation applicable for other processes, in which this procedure is carried out only for certain areas, this solution reliably prevents the risk of recontamination or cross contamination. The hydrohermetic feed system ensures gentle treatment of the product to be processed. A further component of the “hygienic design” of the CSE 170 are the discs which are welded without any gaps. This welding method which has been specially developed by GEA Westfalia Separator reliably prevents dead legs.

The customised function entity consisting of the separator, control unit and sterile package is assembled on a basic frame; it is automated and subjected to a function test (FAT). On site at the user’s premises, it is only necessary for the pipe work for product and operating media to be connected.